A Heartfelt Challenge in Gum Disease. Poor oral health can negate the effects of medication for blood pressure, study finds.

Feb 06 , 2019


Rebecca Hegemann

A Heartfelt Challenge in Gum Disease. Poor oral health can negate the effects of medication for blood pressure, study finds.

MELISSA HEALY melissa.healy@latimes.com

Struggling to bring your high blood pressure under control, even with the help of medications?

Open your mouth and say “aha!”  If you see tooth decay or gums that are sore, bleeding or receding. You may have found the culprit.

Researchers reported last week that in adults whose hypertension was being treated with medications, systolic blood pressure — which measures pressure in the vessels when the heart beats — got higher as the health of their teeth and gums declined.

Compared with hypertensive patients who had no signs of periodontal disease, those with inflamed gums were 20% less likely to have gotten their blood pressure within healthy limits. In addition, patients whose dental health was poor had systolic blood pressure readings that were 3 mm HG higher, on average, than similar patients with healthy gums.

The findings were published in the journal Hypertension.

An estimated 1 in 3 adults in the U.S. — 75 million Americans — are thought to have high blood pressure, putting them at greater risk of heart attack and stroke. Hypertension is a primary or contributing cause of more than 1,000 deaths a day in the United States. Yet only 54% of those with the condition have brought their blood pressure readings under control with some combination of medication, diet and exercise.

The new study is in line with a mountain of research linking gum disease with higher rates of heart, blood vessel and kidney disease — all organs that are affected by high blood pressure. And it breaks new ground by detailing how poor dental health upends efforts to bring hypertension under control.

Indeed, the study found that people with untreated hypertension and healthy gums had blood pressure readings roughly equal to those of people who took medication for their hypertension but also suffered from gum disease.

In other words, poor dental health largely negated the effects of taking blood pressure medication.

The new research doesn’t establish that gum disease causes hypertension and its negative health effects. Many researchers suspect that, like stiff blood vessels, sore and bleeding gums are just one more manifestation of inflammation throughout the body.

Nor does the study show that treating periodontitis will reduce high blood pressure. But it does suggest that, when dental health is poor, the challenge of bringing blood pressure under control will be more expensive and is more likely to fail.

Researchers from Italy scoured the records of 11,753 Americans who participated in the National Health and Nutrition Examination Survey from 2009 to 2014 and were screened for periodontal disease. Some 4,095 of them had been diagnosed with hypertension, of whom 88.5% were taking medication for the condition and 11.5% were not.

Rates of moderate and severe periodontal disease tended to be higher among participants who were men, older, Latino, smokers, and those with less income and education. Participants who were 65 or older and had evidence of long-standing periodontal disease were much more likely than those with less severe and long-standing gum disease to have unchecked high blood pressure — a trend that was particularly evident among Latinos.

In the United States, both hypertension and periodontitis are more common among African Americans and Latinos. Those patient populations also have strikingly higher rates of the diseases linked to both, including heart disease, kidney failure and cerebrovascular diseases such as stroke and certain forms of dementia.

There’s some evidence to suggest African Americans may have a genetic vulnerability to high blood pressure, but it’s controversial. There’s little doubt that access to healthcare differs by race and ethnicity, and that impediments to good medical and dental care play a key role in racial and ethnic health disparities.

Dental care, especially, is expensive and far less likely than medical care to be fully covered by insurance. As a result, economic factors probably play a powerful role in influencing the health of a patient’s gums.

Moreover, many primary care physicians and cardiologists fail to ask their patients about their dental health, or to refer them to dentists unless they are undergoing cardiac procedures and have clear signs of tooth decay.

The study authors wrote that patients with high blood pressure should have their gum health taken into account when they consider their treatment options.

“Our data suggest that all racial/ethnic subgroups, especially Hispanics, might benefit” from such an approach, they wrote. “Conversely, ignoring the additional burden of poor periodontal status on blood pressure might translate into a higher cardiovascular risk in the long term.”

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